British Air Force Typhoon fighter aircraft have operated alongside France's air force in a combined operation on an underground arms cache in Syrian territory employed by the IS group, according to the UK Ministry of Defence.
The site, identified by surveillance, was thought to be containing munitions and bombs, the statement said, and was located in mountains just north of the ancient city of Palmyra in central Syria.
"Our aircraft used laser-guided Paveway IV weapons to target a series of approach shafts down to the depot... preliminary assessments are that the objective was successfully hit," the MoD said.
There was no evidence of any civilian impact in the strike on Saturday evening and each participating jet made a safe return, the defence officials confirmed.
The Typhoon FGR4s were assisted by a Voyager refuelling tanker.
IS - alternatively referred to as Daesh - established militant control over large swathes of Iraq and Syria before its territorial defeat in 2019.
"This strike underscores the UK's leading role, and determination to work closely with allied nations, to eliminate any re-emergence of IS and their dangerous and violent ideologies in the Middle East," the British Defence Secretary John Healey stated.
British military aircraft have carried out patrols over Syria to "deter any efforts to regroup" of IS following its routing at the Baghuz confrontation in 2019, the ministry said.
"I want to thank all the members of British forces participating in this strike for their skill and their bravery," Healey added. "They were part of numerous British personnel deployed over the festive period. This mission, to eliminate militants who threaten our safety, shows how UK forces are always on standby, continuously, protecting the UK within its borders and strong abroad."
In December, the United States armed forces carried out what it termed a "massive strike" against Daesh sites in the country, after an assault claimed the lives of two US troops and a civilian linguist in Palmyra.
The United Nations reports IS still has an estimated 5,000 to 7,000 combatants in Syria and Iraq.
